Dangers of combining antidepressants Effexor and Remeron exposed Major Depressive Disorder s NDA Submission The FDA approval of SEROQUEL XR for MDD was based on a supplemental new drug application (s NDA) comprising findings from two Phase III, placebo-controlled studies that assessed the efficacy and safety of once-daily treatment with SEROQUEL XR as adjunctive treatment in patients with MDD. Maybe it's a necessary combination of a serotonergic effect plus (a non-existent) noradrenergic effect, or some other synergistic mechanism; but it's an add-on, so get adding. There's your data, it's one of the two trials the FDA used to grant the indication. Seroquel was tested as an add-on to SSRIs, and also Effexor and Cymbalta. Combining the antidepressant drugs Effexor and Remeron Zispin, Avanza, Norset, Remergil ruined my life.
The Last Psychiatrist Swallow This How Seroquel XR Works, Part 3 Like Abilify, Seroquel is only indicated for use as a supplement to a failed/failing antidepressant. Mar 14, 2010. Seroquel was tested as an add-on to SSRIs, and also Effexor and Cymbalta. the separation between monotherapy of SSRI and SSRI-augmented with. I should have asked him about switching Mirtazapine for low-dose.
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