Dissociation Constants and Octanol–Water Partition Equilibria for. Extraction by an aqueous two-phase system is a powerful que for separation, concentration, and purification of biomolecules and pharmaceutical products. Oct 30, 2015. The substances studied are ciprofloxacin CIP, danofloxacin. carbon partition coefficient10 and the water solubility.11. However, despite.
Expression of the partition coefficients of a homologous series of 6. In the present study, the partitioning of Ciprofloxacin in aqueous two-phase system of PEG–Na–water has been investated. Expression of the partition coefficients of a homologous series of 6-fluoroquinolones on ResearchGate, the professional network for scientists.
Determination of pKa values of active pharmaceutical ingredients Si vous êtes membre de la communauté CNRS (Centre National de la Recherche Scientifique) ou ESR français (Ensenement Supérieur et Recherche), la barre de recherche permet d’accéder à Refdoc, catalogue contenant plus de 53 millions de références bibliographiques. With the search bar you can access directly and consult over 53 million bibliographic records for free. Water partition coefficient, dissociation constants, vapor. governs solubility, absorption, distribution, metabolism and elimination. Method. Ref. Ciprofloxacin.
A comparative study of ofloxacin and ciprofloxacin erythrocyte distribution (thermodynamic partition coefficient) and the diffusion through the lipid bilayers (‘hydrophobic pathway’) of entry has been considered here. A comparative study of ofloxacin and ciprofloxacin erythrocyte. The partition coefficients obtained from the linear relationship between plasma and erythrocyte.
Determination and Correlation of 1-Octanol/Water Partition Coefficients. We have used a recently described animal model to characterize the ocular pharmacokinetics of sparfloxacin in vitreous humor of uninfected albino rabbits following systemic administration and direct intraocular injection. Determination and Correlation of 1-Octanol/Water Partition Coefficients for Six Quinolones from 293.15 K to 323.15 K. ciprofloxacin, pefloxacin and pipemidic acid.
Pharmacokinetics of Sparfloxacin in the Serum and Vitreous Humor. The relationships of lipophilicity, protein binding, and molecular weht to the penetration and elimination of sparfloxacin were compared to those of ciprofloxacin, fleroxacin, and ofloxacin. Penetration of sparfloxacin, ciprofloxacin, fleroxacin, and ofloxacin into, and elimination. A Relationship between the partition coefficients for ciprofloxacin •.