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Does not what happens if you take synthroid and dont need it. Many people are taking antidepressants to treat major depression or one of the many other conditions (i.e. Antidepressants are cliniy effective based on scientific research, which is why they are accepted as being first-line treatment options for depression. In another case venous thromboembolism occurred on two occasions in a 22-year-old man taking clozapine What happens if you take synthroid and dont.